Representative
Publications:
Kiertscher SM, Luo J, Dubinett SM, Roth MD.
Tumors promote altered maturation and early
apoptosis of monocyte-derived dendritic cells.
J. Immunol. 2000; 164(3):1269-1276.
Roth
MD, Gitlitz BL, Kiertscher SM, Park AN, Mendenhall
M, Moldawer N, Figlin RA. Granulocyte-macrophage
colony-stimulating factor and interleukin-4
enhance the number and antigen-presenting
cell activity of circulating CD14+ and CD83+
cells in cancer patients. Cancer Res. 2000;
60(7):1934-1941.
Thoma-Uszynski
S, Kiertscher SM, Ochoa MT, Bouis DA, Norgard
MV, Miyake K, Godowski PJ, Roth MD, Modlin
RL. Activation of Toll-like receptor 2 on
human dendritic cells triggers induction of
IL-12, but not IL-10. J. Immunol. 2000; 165(7):3804-3810.
Roth
MD, Cheng Q, Harui A, Basak S, Mitani K, Low
TA, Kiertscher SM. Helper-dependent adenoviral
vectors efficiently express transgenes in
human DC, but still stimulate antiviral immune
responses. J. Immunol. 2002; 169(8):4651-4656.
Kiertscher
SM, Gitlitz BJ, Figlin RA, Roth MD. GM-CSF
and IL-4 expand and activate Type-1 dendritic
cells (DC1) when administered in vivo to cancer
patients. Int. J. Cancer 2003; 107(2):256-261.
Liau
LM, Prins RM, Kiertscher SM, Odesa SK, Kremen
TJ, Giovannone AJ, Lin J-W, Chute DJ, Mischel
PS, Cloughsey TF, Roth MD. Dendritic cell
vaccination in Glioblastoma patients induces
differential systemic and intracranial T cell
responses mediated by CNS tumor microenvironment.
Clin. Cancer Res. 2005; 11(15):5515-5525.
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