Representative
Publications:
Effects of Marijuana and Cocaine on the Lung
Barsky SH, Roth MD, Kleerup EC, Simmons M, Tashkin
DP. Similar molecular alterations in bronchial
epithellium are observed in habitual smokers
of marijuana, cocaine and/or tobacco. J National
Cancer Institute 90:1198-1204, 1998.
Roth
MD, Arora A, Barsky SH, Kleerup EC, Simmons
M, Tashkin DP. Visual and pathologic evidence
of injury to the airways of young marijuana
smokers. Am J Respir Crit Care Med 157:928-937,
1998.
Matthias
P, Tashkin DP, Marques-Magallanes JA, Wilkins
JN, Simmons MS. Effects of varying marijuana
potency on deposition of tar and D9-THC in
the lung during smoking. Pharmacol Biochem
Behav 58:1045-1050, 1997.
Tashkin
DP, Kleerup EC, Hoh C, Kim K-J, Webber M,
Gil E. Effects of "crack" cocaine
on pulmonary alveolar permeability. Chest
112:327-335, 1997.
Fligiel
SEG, Roth MD, Kleerup EC, Barsky SH, Simmons
MS, Tashkin DP. Tracheobronchial histopathology
in habitual smokers of cocaine, marijuana
and/or tobacco. Chest 112:319-326, 1997.
Marques-Magallanes
JA, Koyal SN, Cooper CB, Kleerup EC, Tashkin
DP. Impact of habitual cocaine smoking on
the physiological response to maximum exercise.
Chest 112:1008-1016, 1997.
Baldwin
GC, Tashkin DP, Buckley DM, Park AN, Dubinett
SM, Roth MD. Habitual smoking of marijuana
and cocaine impairs alveolar macrophage function
and cytokine production. J Respir Crit Care
Med 156:1606-1613, 1997.
Baldwin
GC, Buckley DM, Roth MD, Kleerup EC, Tashkin
DP. Acute activation of circulating PMNs following
in vivo administration of cocaine: A potential
etiology for pulmonary injury. Chest 1997;
111:698-705.
Kleerup
EC, Wong Maylene, Marques JA, Goldman MD,
Tashkin MD. Acute effects of intravenous cocaine
on pulmonary artery pressure and cardiac index
in habitual crack users. Chest 111:30-35,
1997.
Tashkin
DP, Kleerup EC, Koyal S, Marques JA, Goldman
M. Acute effects of inhaled and intravenous
cocaine on airway dynamics. Chest 110:904-910,
1996.
Early
Intervention in COPD (the Lung Health Study)
Tashkin DP, Altose MD, Connett JE, Kanner
RE, Lee WW, Wise RA, for the Lung Health Study
Research Group. Methacholine reactivity predicts
changes in lung function over time in smokers
with early COPD. Am J Respir Crit Care Med
153:1802-1811, 1996.
Anthonisen
NR, Connett JE, Kiler JP, Altose MD, Bailer
WC, Buist AS, Conway WA, Enright PA. Kanner
RE, O'Hara P, Owens GR, Scanlon PD, Tashkin
DP, Wise RA for the Lung Health Study Research
Group. Effects of smoking intervention and
the use of an anticholinergic bronchod.lator
on the rate of deline in FEV1. The Lung Health
Study. JAMA 272:1497-1505, 1994.
Microelectronic
Monitoring of Adherence
Tashkin DP. Microelectronic Adherence Monitors
for Metered-Dose Inhalers: Who Monitors the
Monitors? (Editorial) J Allergy Clin Immunol
1999 104:22-24.
Simmons
MS, Nides MA, Kleerup, EC, Chapman KR, Milgrom
H, Rand CS, Spector SL, Tashkin DP. Validation
of the DoserTM, a new device for monitoring
metered-dose inhaler use. J Allergy Clin Immunol
102:409-413, 1998.
Small
Airways
Goldin JG, Tashkin DP, Kleerup EC, Greaser
LE, Haywood UM, Sayre JW, Simmons MD, Suttorp
M, Colice GL, Vander Burgt JA, Aberle DR.
Comparative effects of HFA- and CFC-beclomethasone
diproprionate inhalation on small airways:
assessment using functional helical thin-section
computed tomography. J Allergy Clin Immunol
1999; 104:S258-267.
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