Areas of Interest - Basic Research

Host Defense

Role of antimicrobial peptides in airway clearance of pathogens. Airway surface contains many antimicrobial components including high concentrations of lysozyme, lactoferrin and other antimicrobial peptides and proteins. We are exploring the interactions of these antimicrobial components with respiratory pathogens, and the abnormalities of airways secretions in various lung diseases.

Tomas Ganz
- Structure and function of defensins and other antimicrobial peptides
- Abnormalities of nasal and airways secretions in cystic fibrosis and nasal carriage of Staph. aureus

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